Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512410 | 0.83 | KCNH2 (0.44) | KCNH2CNR1CNR2 | |
| SCHEMBL5509547 | 0.78 | CYP2C9 (0.45) | KCNH2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL590586 | 0.76 | KCNH2 (0.46) | KCNH2CNR1CNR2ALDH1A1NPC1 | |
| SCHEMBL5508579 | 0.75 | ALDH1A1 (0.47) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5508574 | 0.75 | ALDH1A1 (0.47) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL633958 | 0.75 | KCNH2 (0.54) | KCNH2CNR1CNR2ALDH1A1 | |
| SCHEMBL591768 | 0.74 | KDM4E (0.51) | KCNH2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5506636 | 0.73 | KCNH2 (0.56) | KCNH2KMT2AKDM4E | |
| SCHEMBL5507933 | 0.73 | KCNH2 (0.45) | KCNH2CNR1CNR2KMT2AMEN1 | |
| SCHEMBL632652 | 0.72 | KCNH2 (0.39) | KCNH2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |