Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505341 | 0.89 | CYP2D6 (0.34) | KDM1A | |
| SCHEMBL5226012 | 0.87 | — | — | |
| SCHEMBL5114413 | 0.85 | HTR2C (0.33) | KDM1A | |
| SCHEMBL5507880 | 0.80 | PIM1 (0.35) | — | |
| SCHEMBL5221409 | 0.79 | OPRM1 (0.37) | — | |
| SCHEMBL5507974 | 0.79 | MKNK1 (0.36) | KDM1A | |
| SCHEMBL5506174 | 0.78 | KDM1A (0.35) | KDM1A | |
| SCHEMBL5507708 | 0.76 | LMNA (0.40) | KDM1A | |
| SCHEMBL5125807 | 0.73 | CYP2D6 (0.37) | KDM1A | |
| SCHEMBL12537100 | 0.71 | KDM1A (0.47) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846400-A2 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-24 | — | — | EP | claimed |
| WO-2006074388-A2 | TRICYCLIC δ-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-13 | — | — | WO | claimed |
| EP-1846400-A2 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006074388-A2 | TRICYCLIC δ-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-13 | — | — | WO | disclosed |