SCHEMBL5516980

SCHEMBL5516980

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(Cl)[C@@H](OC(C)=O)C[C@@]21C

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 8/20 0.81
▸ USP2 O75604 7/20 0.81
▸ NR3C1 P04150 6/20 0.81
▸ PGR P06401 6/20 0.81
▸ ADORA3 P0DMS8 3/20 0.81
▸ HIF1A Q16665 2/20 0.81
▸ CNR1 P21554 2/20 0.81
▸ AR P10275 2/20 0.81
▸ CHRM1 P11229 1/20 0.81
▸ TBXA2R P21731 1/20 0.81
▸ NR1I2 O75469 2/20 0.69
▸ MAPT P10636 2/20 0.69
▸ DRD2 P14416 1/20 0.69
▸ OPRD1 P41143 1/20 0.69
▸ LMNA P02545 4/20 0.59
▸ CYP2C9 P11712 3/20 0.59
▸ ABCB11 O95342 2/20 0.59
▸ CYP2D6 P10635 2/20 0.59
▸ MLNR O43193 1/20 0.59
▸ CYP3A5 P20815 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102220 0.95 CYP3A4 (0.83) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL8832311 0.93 CYP3A4 (0.81) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL13524493 0.92 CYP3A4 (0.83) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL4929631 0.92 CYP3A4 (0.77) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL1217308 0.92 CYP3A4 (0.77) CYP3A4USP2NR3C1PGRADORA3
Water SCHEMBL1219475 0.91 CYP3A4 (0.76) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL7593 0.90 NR3C1 (0.82) CYP3A4USP2NR3C1PGRADORA3
Beclomethasone Dipropionate SCHEMBL2407947 0.90 CYP3A4 (0.86) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL11292765 0.90 CYP3A4 (0.76) CYP3A4USP2NR3C1PGRADORA3
Beclomethasone Dipropionate SCHEMBL6055708 0.89 CYP3A4 (1.00) CYP3A4USP2NR3C1PGRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117030904-B Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-12-19 — — CN claimed
EP-3915568-A1 MUCOADHESIVE COMPOSITION FOR USE IN THE TREATMENT OF ORAL WOUND Piccolo Federico (IT) 2021-12-01 — — EP claimed
US-5897878-A ORALLY ADMINISTERING DELIVERY SYSTEM IN WHICH FLUID IMBIBITION CAUSES HYDROPHILIC POLYMER TO AGGREGATE IN SITU IN PRESENCE OF POLYHYDROXY COMPOUND AND CAUSES PUSH LAYER TO ABSORB FLUID AND DELIVER AGGREGATES CONTAINING STEROID ALZA CORPORATION (US) 1999-04-27 — — US claimed
US-5650170-A Dosage form for delivering drug at a controlled rate to the intestine and to the colon ALZA CORPORATION (US) 1997-07-22 — — US claimed
EP-0521074-B1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORP (US) 1994-03-02 — — EP claimed
US-5178866-A DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1993-01-12 — — US claimed
EP-0521074-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. ALZA CORP (US) 1993-01-07 — — EP claimed
WO-1991014426-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1991-10-03 — — WO claimed
EP-3915568-A1 MUCOADHESIVE COMPOSITION FOR USE IN THE TREATMENT OF ORAL WOUND Piccolo Federico (IT) 2021-12-01 — — EP disclosed
US-20070207204-A1 Dosage Form for Time-Varying Patterns of Drug Delivery ALZA CORPORATION (US) 2007-09-06 — — US disclosed
EP-1492509-A1 DOSAGE FORM PROVIDING TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA Corporation (US) 2005-01-05 — — EP disclosed
US-20030125714-A1 Dosage form for time-varying patterns of drug delivery ALZA CORPORATION 2003-07-03 — — US disclosed
WO-2003051341-A1 DOSAGE FORM FOR PROVIDING TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 2003-06-26 — — WO disclosed
US-5785994-A OSMOTIC DOSAGE FORM FOR CONTROLLED DRUG RELEASE ALZA CORPORATION (US) 1998-07-28 — — US disclosed
US-5178866-A DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1993-01-12 — — US disclosed
EP-0521074-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. ALZA CORP (US) 1993-01-07 — — EP disclosed
US-5156850-A DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 1992-10-20 — — US disclosed
WO-1992004011-A1 DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 1992-03-19 — — WO disclosed
WO-1991014426-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1991-10-03 — — WO disclosed
US-4904474-A Delivery of drug to colon by oral disage form ALZA CORPORATION (US) 1990-02-27 — — US disclosed
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