Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL552115 | 1.00 | MEN1 (0.41) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL4974939 | 0.99 | MEN1 (0.40) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL4978507 | 0.99 | MEN1 (0.40) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL551878 | 0.89 | MEN1 (0.44) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL552116 | 0.89 | MEN1 (0.44) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL2918472 | 0.88 | ATM (0.39) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2891824 | 0.88 | MEN1 (0.42) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| Lithium Ion SCHEMBL5499662 | 0.87 | MEN1 (0.37) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| SCHEMBL5502939 | 0.87 | MEN1 (0.37) | MEN1KMT2ARAB9AALDH1A1MTNR1A | |
| Lithium Ion SCHEMBL4978502 | 0.87 | MEN1 (0.37) | MEN1KMT2ARAB9AALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110689-B2 | Benzanilides with insecticidal activity | BAYER CROPSCIENE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | US | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
| US-20090118375-A1 | Optically active phthalamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-1893567-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | Bayer CropScience AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | NAKAO HAYAMI | 2008-02-28 | — | — | US | disclosed |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | NAKAO HAYAMI | 2008-02-28 | — | — | US | disclosed |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | NAKAO HAYAMI | 2008-02-28 | — | — | US | disclosed |
| EP-1814874-A1 | N-HETEROCYCLYL PHTHALIC ACID DIAMIDES AS INSECTICIDES | Bayer CropScience AG (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1789382-A2 | OPTICALLY ACTIVE PHTHALAMIDES | Bayer CropScience AG (DE) | 2007-05-30 | — | — | EP | disclosed |
| EP-1782689-A1 | OPTICALLY ACTIVE PHTHALAMIDE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL INSECTICIDE, AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006133823-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006053643-A1 | N-HETEROCYCLYL PHTHALIC ACID DIAMIDES AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006024412-A2 | OPTICALLY ACTIVE PHTHALAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | CBR3, HCN3, HAX1 | MEN1 3108/4885KMT2A 1629/4885RAB9A 766/4885 |
| US-20090118375-A1 | Optically active phthalamides | CRYZ, CRY1, CRY2 | MEN1 417/4885KMT2A 127/4885RAB9A 1005/4885 |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | MEN1 4180/4885KMT2A 657/4885RAB9A 405/4885 |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | CRY1, CNPY2, H1-0 | MEN1 355/4885KMT2A 25/4885RAB9A 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.