Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.71 |
| ▸ | CTSL | P07711 | 11/20 | 0.71 |
| ▸ | CTSB | P07858 | 7/20 | 0.71 |
| ▸ | CTSK | P43235 | 6/20 | 0.71 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525219 | 0.90 | CTSS (0.76) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5524529 | 0.85 | ATM (0.54) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5524522 | 0.85 | ATM (0.54) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5523569 | 0.83 | KYNU (0.57) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5523572 | 0.83 | KYNU (0.57) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5522007 | 0.83 | CTSL (0.58) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6183068 | 0.81 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6181799 | 0.81 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6182543 | 0.81 | CTSS (1.00) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL5527004 | 0.79 | CTSS (0.74) | CTSSCTSLCTSBCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | CTSV, CTSB, CTSS | CTSS 3/4885CTSL 9/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.