SCHEMBL5522249

SCHEMBL5522249

C=C(CCC(C)N(C(C)O)C(C)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRM1 Q13255 1/20 0.35
GRM2 Q14416 1/20 0.35
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1972700 0.80 CHRNB2 (0.47)
SCHEMBL27792 0.77 ALDH1A1 (0.45) TET2TET3TET1GRIK1GRIK2
SCHEMBL2121261 0.77 GABRP (0.33) TET2TET3TET1GRIK1GRIK2
Trimethylammonium SCHEMBL8162324 0.76 ALDH1A1 (0.41) TET2TET3TET1GRIK1GRIK2
Hydrochloric Acid SCHEMBL1961274 0.75 ALDH1A1 (0.43) TET2TET3TET1GRIK1GRIK2
SCHEMBL23251 0.74 CA1 (0.48) TET2TET3TET1GRIK1GRIK2
Trimethylammonium SCHEMBL5376671 0.74 ALDH1A1 (0.39) TET2TET3TET1GRIK1GRIK2
Trimethylammonium SCHEMBL309601 0.74 ALDH1A1 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL2121893 0.74 FDPS (0.33) TET2TET3TET1
Itaconate SCHEMBL5874230 0.74 ALOX15 (0.54) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999167-B2 Composite porous membrane and process for producing the same ASAHI KASEI MEDICAL CO., LTD. (JP) 2015-04-07 US disclosed
US-20070029256-A1 Composite porous membrane and process for producing the same ASAHI KASEI MEDICAL CO., LTD. (JP) 2007-02-08 US disclosed