Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.67 |
| ▸ | TOP2A | P11388 | 2/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.58 |
| ▸ | CTH | P32929 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522739 | 1.00 | HKDC1 (0.67) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL30816738 | 1.00 | HKDC1 (0.67) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL8738064 | 0.86 | CTH (0.55) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL29852200 | 0.86 | CTH (0.55) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL941093 | 0.81 | TOP2A (0.70) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL9319994 | 0.81 | TOP2A (0.70) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL941092 | 0.81 | TOP2A (0.70) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL27178963 | 0.81 | TOP2A (0.70) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL7086491 | 0.81 | AGTR1 (0.62) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL7086789 | 0.81 | AGTR1 (0.62) | HKDC1TOP2AHSP90AA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596037-B1 | RADIOPHARMACEUTICAL PRODUCT HAVING IN PARTICULAR A CEREBRAL TROPISM COMPRISING A TRANSITION METAL NITRIDE COMPLEX, AND PREPARATION METHOD THEREFOR | CIS BIO INT (FR) | 2001-05-02 | — | — | EP | claimed |
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | CYP51A1, TUBA3C, PIGO | HKDC1 4650/4885TOP2A 1011/4885HSP90AA1 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.