Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573229 | 0.83 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ATDP1CA12 | |
| SCHEMBL28134387 | 0.81 | PDK1 (0.51) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL54917 | 0.79 | L3MBTL1 (0.75) | L3MBTL1MEN1KMT2ACA12CA1 | |
| SCHEMBL5201283 | 0.77 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2ATDP1CA12 | |
| SCHEMBL751975 | 0.74 | MTNR1B (0.47) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL202154 | 0.73 | CA12 (0.53) | L3MBTL1MEN1KMT2ACA12CA1 | |
| SCHEMBL98001 | 0.73 | GAA (0.56) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3760341 | 0.73 | POLB (0.57) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12226380 | 0.71 | L3MBTL1 (0.61) | L3MBTL1MEN1KMT2ATDP1CA12 | |
| SCHEMBL10962729 | 0.70 | HPGD (0.62) | L3MBTL1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179832-B2 | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2007-02-20 | — | — | US | disclosed |
| US-20060079521-A1 | Glycogen synthase kinase 3beta inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079521-A1 | Glycogen synthase kinase 3beta inhibitor, composition and process for the preparation thereof | GSK3B, GSK3A, GYS2 | L3MBTL1 4202/4885MEN1 4192/4885KMT2A 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.