Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 8/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 8/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54917 | 0.85 | L3MBTL1 (0.75) | L3MBTL1MAPTALDH1A1CA12CA1 | |
| SCHEMBL4573229 | 0.82 | L3MBTL1 (0.52) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL3129785 | 0.81 | PDK1 (0.67) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL6655436 | 0.80 | PDK1 (0.44) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL18086475 | 0.79 | L3MBTL1 (0.59) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL202154 | 0.79 | CA12 (0.53) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20124849 | 0.78 | MAPT (0.57) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL5523100 | 0.77 | L3MBTL1 (0.47) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL27893900 | 0.76 | L3MBTL1 (0.55) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL5199230 | 0.76 | L3MBTL1 (0.46) | L3MBTL1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-11-29 | — | — | US | claimed |
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | claimed |
| US-20070275968-A1 | Substituted Biphenyl Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | COL2A1, COL1A1, FGFR3 | L3MBTL1 2263/4885PDK1 4247/4885PDK2 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.