Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418287 | 0.86 | CA1 (0.44) | HSP90AA1HSP90AB1NPC1RAB9ALMNA | |
| SCHEMBL1628413 | 0.79 | KEAP1 (0.61) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL7091942 | 0.78 | NPC1 (0.45) | ALDH1A1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4860020 | 0.78 | PTGS1 (0.63) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL5637788 | 0.77 | KEAP1 (0.62) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL4739158 | 0.75 | RAB9A (0.59) | ARALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22979854 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10744595 | 0.75 | CA12 (0.61) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL22589850 | 0.75 | NR3C1 (0.44) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL26125104 | 0.73 | HTT (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070071782-A1 | 2-Cyanobenzenesulfonamides for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-1670752-A1 | 2-CYANOBENZENESULFONAMIDES FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005035486-A1 | 2-CYANOBENZENESULFONAMIDES FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070071782-A1 | 2-Cyanobenzenesulfonamides for combating animal pests | MSR1, CHRM2, CBS | NR3C1 4120/4885PGR 4737/4885NR3C2 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.