Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.34 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360708 | 1.00 | APP (0.34) | APPUSP28USP25PDE4DHTT | |
| SCHEMBL14408048 | 0.82 | PIN1 (0.37) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL14408050 | 0.82 | PIN1 (0.37) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3924177 | 0.82 | PIN1 (0.37) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5361040 | 0.82 | PIN1 (0.37) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5368378 | 0.76 | MEN1 (0.34) | USP28USP25HTTABCB1TP53 | |
| SCHEMBL5359985 | 0.75 | APP (0.32) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5265250 | 0.74 | MAPT (0.47) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5268319 | 0.71 | PDE4A (0.38) | APPPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7412977 | 0.70 | SNCA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276147-A1 | Synthesis of Oligomeric Epicatechin- and Catechin-Derived Procyanidins | KOZIKOWSKI ALAN P | 2007-11-29 | — | — | US | claimed |