Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532810 | 0.70 | MMP1 (0.62) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL1656130 | 0.70 | MMP1 (0.62) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL10794785 | 0.63 | MMP13 (0.56) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL19640805 | 0.63 | ALDH1A1 (0.55) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL1352340 | 0.63 | PKM (0.77) | ALDH1A1PKMMAPTSMN1; SMN2TSHR | |
| SCHEMBL8060759 | 0.63 | PKM (0.64) | MMP1MMP9MMP3MMP7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7349934 | 0.62 | MMP1 (0.75) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL7352806 | 0.62 | MMP1 (0.79) | MMP1MMP9MMP13MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL10798777 | 0.62 | MMP13 (0.55) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL10042202 | 0.62 | MMP1 (0.65) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768979-A1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008303-A1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-01-26 | — | — | WO | disclosed |