Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.55 |
| ▸ | BLM | P54132 | 6/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23549436 | 0.81 | LMNA (0.64) | ALDH1A1MAPTKDM4EBLMMAPK1 | |
| SCHEMBL27807830 | 0.79 | ALDH1A1 (0.70) | ALDH1A1MAPTTDP1KDM4EBLM | |
| SCHEMBL27807831 | 0.79 | ALDH1A1 (0.70) | ALDH1A1MAPTTDP1KDM4EBLM | |
| SCHEMBL3235781 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EADRB2BLMADRB1 | |
| SCHEMBL8684302 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL6300038 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL6298892 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL8848489 | 0.76 | TDP1 (0.46) | ALDH1A1MAPTTDP1KDM4EADRB2 | |
| Epinephrine SCHEMBL19994728 | 0.74 | KDM4E (0.79) | ALDH1A1MAPTTDP1KDM4EADRB2 | |
| SCHEMBL4242515 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205425-B2 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | CHISSO CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | SHIBASAKI MASAKATSU | 2007-03-15 | — | — | US | disclosed |
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-0947498-B1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORP (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6632955-B1 | Optically active 1-substituted phenyl-2-nitro alcohol derivatives which are useful pharmaceutical intermediates. Enantiomotphs active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohol such as albutramin and | CHISSO CORPORATION (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0947498-A1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORPORATION (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | ALDH1A1 29/4885MAPT 2856/4885TDP1 2914/4885 |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | ALDH1A1 29/4885MAPT 2856/4885TDP1 2914/4885 |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, SARM1 | ALDH1A1 24/4885MAPT 2862/4885TDP1 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.