Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529045 | 0.90 | ADORA3 (0.34) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL5533682 | 0.76 | NPC1 (0.46) | KMT2AMEN1TSHRMAPK1ADORA2A | |
| SCHEMBL5529049 | 0.68 | LTA4H (0.44) | ADORA2A | |
| SCHEMBL5528127 | 0.67 | ADORA2A (0.45) | KMT2AMEN1HTTALDH1A1CYP1A2 | |
| SCHEMBL4907336 | 0.67 | ADORA2A (0.43) | KDM4EALDH1A1NPSR1MAPTTSHR | |
| SCHEMBL1326595 | 0.67 | ALDH1A1 (0.54) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL4907346 | 0.65 | ADORA2A (0.41) | KMT2AMEN1MTORPIK3CAALDH1A1 | |
| SCHEMBL2634918 | 0.63 | MEN1 (0.43) | KMT2AMEN1MTORPIK3CAPIK3R1 | |
| SCHEMBL11123139 | 0.63 | HPGD (0.40) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL5529061 | 0.62 | POLB (0.35) | HTTKDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | BTK, SYK, LYN | KMT2A 1195/4885MEN1 2835/4885HTT 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.