Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529049 | 0.90 | LTA4H (0.44) | ADORA2AADORA1LTA4H | |
| SCHEMBL5533681 | 0.76 | KMT2A (0.41) | ADORA2AMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL5529045 | 0.68 | ADORA3 (0.34) | ADORA2AADORA3ADORA1MEN1KMT2A | |
| SCHEMBL5528127 | 0.67 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1MEN1 | |
| SCHEMBL1326596 | 0.67 | ALDH1A1 (0.69) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL14233404 | 0.66 | TLR9 (0.71) | MEN1KMT2ATLR9TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL9013588 | 0.65 | NPC1 (0.55) | NPC1RAB9A | |
| SCHEMBL11898739 | 0.65 | NPC1 (0.97) | NPC1RAB9ALTA4H | |
| SCHEMBL6452945 | 0.64 | NPC1 (0.79) | NPC1RAB9ATP53TSHRMAPK1 | |
| SCHEMBL4907342 | 0.64 | ADORA2A (0.56) | NPC1RAB9AADORA2AADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | BTK, SYK, LYN | NPC1 4530/4885RAB9A 1164/4885ADORA2A 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.