Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | BACE1 | P56817 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847612 | 0.89 | KMT2A (0.59) | ACHEBACE1KMT2ADRD4LMNA | |
| SCHEMBL6418433 | 0.88 | DRD4 (0.56) | ACHEBACE1KMT2ADRD4LMNA | |
| SCHEMBL1857852 | 0.84 | GPR119 (0.53) | KMT2ADRD4LMNAALDH1A1MAPT | |
| SCHEMBL4214296 | 0.84 | CHKA (0.50) | KMT2ADRD4LMNAALDH1A1HPGD | |
| SCHEMBL5533747 | 0.81 | DRD4 (0.50) | ACHEBACE1KMT2ADRD4CARM1 | |
| SCHEMBL8081164 | 0.81 | ACHE (0.68) | ACHEBACE1KMT2ACARM1PRMT6 | |
| SCHEMBL14488050 | 0.81 | ALDH1A1 (0.53) | KMT2ALMNASLC6A2SLC6A3TDP1 | |
| SCHEMBL15521641 | 0.79 | KEAP1 (0.48) | KMT2AALDH1A1SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL14487845 | 0.79 | CHRNB2 (0.54) | KMT2ALMNASLC6A2SLC6A3TDP1 | |
| SCHEMBL3962996 | 0.78 | SMN1; SMN2 (0.56) | ACHEBACE1KMT2ADRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232825-B2 | Phenylaminopyrimidine derivatives and methods of use | CHEN GUOQING P | 2007-06-19 | — | — | US | disclosed |