Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526963 | 0.93 | ALOX5 (0.42) | RXFP1ALOX5MAPTNAMPTNTRK1 | |
| SCHEMBL5535769 | 0.80 | GABRP (0.42) | MAPTNAMPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5532547 | 0.79 | MAPT (0.45) | MAPTSMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL5533925 | 0.78 | MAPT (0.46) | ALOX5MAPTNAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3847524 | 0.76 | FAAH (0.54) | RXFP1MAPTNAMPTSMN1; SMN2KDM4E | |
| SCHEMBL5535174 | 0.75 | MAPT (0.46) | ALOX5MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3845545 | 0.74 | TUBB4A (0.55) | RXFP1MAPTNAMPTKCNQ3KCNQ2 | |
| SCHEMBL3850606 | 0.72 | TUBB4A (0.55) | RXFP1MAPTNAMPT | |
| SCHEMBL4029345 | 0.72 | POLB (0.45) | MAPTNPC1HPGDRAB9AMEN1 | |
| SCHEMBL3824082 | 0.71 | TUBB4A (0.53) | ALOX5MAPTNAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |