Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779679 | 0.82 | APP (0.71) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL8897898 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL1084153 | 0.81 | CYP1A2 (0.79) | CYP1A2CYP3A4HSD17B10KDM4EUSP2 | |
| SCHEMBL4867969 | 0.81 | MAPT (0.59) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL28414968 | 0.80 | LDHA (0.62) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL31649377 | 0.78 | KDM4E (0.56) | CYP1A2CYP3A4HSD17B10KDM4EUSP2 | |
| SCHEMBL3110568 | 0.77 | APP (0.71) | CYP1A2CYP3A4HSD17B10USP2CYP2C19 | |
| SCHEMBL11246544 | 0.76 | LDHA (1.00) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL23723479 | 0.74 | KMT2A (0.70) | CYP1A2CYP3A4HSD17B10KDM4ELDHA | |
| SCHEMBL8890175 | 0.74 | PDE5A (0.55) | CYP1A2CYP3A4HSD17B10KDM4ELDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | CYP1A2 4734/4885CYP3A4 4532/4885HSD17B10 3870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.