Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531303 | 0.92 | PKM (0.56) | NPSR1L3MBTL1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5530519 | 0.83 | POLB (0.58) | NPSR1HTTALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5530231 | 0.82 | POLB (0.58) | L3MBTL1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL5531686 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTGAAMEN1 | |
| SCHEMBL5534284 | 0.78 | ABCC1 (0.55) | NPSR1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL5527980 | 0.76 | MAPT (0.71) | NPSR1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL21663545 | 0.75 | NPSR1 (0.88) | NPSR1L3MBTL1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5534594 | 0.75 | HTT (0.72) | HTTALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5529178 | 0.74 | POLB (0.55) | ALDH1A1SMN1; SMN2MAPTGAAKMT2A | |
| SCHEMBL18194711 | 0.74 | NPSR1 (0.66) | NPSR1L3MBTL1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | NPSR1 62/4885L3MBTL1 3309/4885HTT 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.