SCHEMBL5540677

SCHEMBL5540677

O=C(NN=Cc1ccc[nH]1)C1CC2CCCC(C2)C1.[CH2]

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.49
▸ RAB9A P51151 5/20 0.49
▸ LMNA P02545 3/20 0.49
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ NR2F2 P24468 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ POLB P06746 2/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ GAA P10253 1/20 0.47
▸ RECQL P46063 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031005 0.74 MEN1 (0.58) MAPTRAB9ALMNAL3MBTL1NPC1
SCHEMBL5031002 0.74 MEN1 (0.58) MAPTRAB9ALMNAL3MBTL1NPC1
SCHEMBL9655956 0.72 MAPT (0.63) MAPTRAB9ALMNANPC1MEN1
SCHEMBL9655953 0.72 MAPT (0.63) MAPTRAB9ALMNANPC1MEN1
SCHEMBL10335322 0.72 MAPT (0.63) MAPTRAB9ALMNANPC1MEN1
SCHEMBL14757299 0.71 MAPT (0.75) MAPTRAB9ALMNAL3MBTL1NPC1
SCHEMBL14107064 0.69 MEN1 (0.43) MAPTRAB9ALMNAL3MBTL1NPC1
SCHEMBL10511247 0.68 RAB9A (0.74) MAPTRAB9ALMNANPC1MEN1
SCHEMBL31005089 0.67 MAPT (0.78) MAPTRAB9ALMNAL3MBTL1NPC1
SCHEMBL14757390 0.66 MAPT (1.00) MAPTRAB9ALMNAL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070207093-A1 Hydrazone derivatives and uses thereof LINQUAGEN CORP. 2007-09-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207093-A1 Hydrazone derivatives and uses thereof TAS2R1, TAS2R5, TAS1R1 MAPT 4421/4885RAB9A 2563/4885LMNA 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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