Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 13/20 | 0.65 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | CDC42 | P60953 | 1/20 | 0.65 |
| ▸ | RAC1 | P63000 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134150 | 1.00 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL1448280 | 1.00 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL29993492 | 1.00 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL29993475 | 1.00 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL13810650 | 0.89 | AKR1C3 (0.53) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL12744140 | 0.88 | AKR1C3 (0.51) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11470486 | 0.85 | AKR1C3 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL10025981 | 0.83 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL1217681 | 0.83 | AKR1B1 (0.69) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| Ammonia Solution, Strong SCHEMBL11721423 | 0.83 | AKR1C3 (0.67) | AKR1C3AKR1C2PTGS2PTGS1CDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322099-B | Naproxen-cinnamic acid derivative and application thereof in preparation of medicines for treating LPS-induced inflammation | 五邑大学 | 2024-04-02 | — | — | CN | claimed |
| CN-115322099-A | Naproxen-cinnamic acid derivatives and application thereof in preparation of drugs for treating LPS (LPS) -induced inflammation | 五邑大学 | 2022-11-11 | — | — | CN | claimed |
| CN-110396156-B | Stimulus-response type spiral polyacetylene infrared radiation material and preparation method thereof | 东南大学 | 2021-09-28 | — | — | CN | claimed |
| US-6740256-B1 | COMPOSED OF THE COMPOUND OF (N,N'-DIETHYL (S)-2-(6-(4-(4'-ALKOXYPHENYL)BENZOYLOXY)-2-NAPHTHYL)PROPANAMIDE | CHUNGHWA PICTURE TUBES, LTD. (TW) | 2004-05-25 | — | — | US | claimed |
| EP-0095901-B1 | PROCESS FOR THE PREPARATION OF (D) 2-(D-METHOXY-2-NAPHTHYL) PROPIONIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND NEW INTERMEDIATES THEREFOR | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1992-09-09 | — | — | EP | claimed |
| EP-0095901-A1 | Process for the preparation of (d) 2-(d-methoxy-2-naphthyl) propionic acid and pharmaceutically acceptable salts thereof and new intermediates therefor | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-12-07 | — | — | EP | claimed |
| JP-2053819-A | — | — | None | — | — | JP | disclosed |
| JP-3031393-A | — | — | None | — | — | JP | disclosed |
| JP-63166850-A | — | — | None | — | — | JP | disclosed |
| JP-59204152-A | — | — | None | — | — | JP | disclosed |
| EP-3160514-B1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | REILEY PHARMACEUTICALS INC (US) | 2024-07-31 | — | — | EP | disclosed |
| US-20240190790-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | REILEY PHARMACEUTICALS INC (US) | 2024-06-13 | — | — | US | disclosed |
| CN-115322099-B | Naproxen-cinnamic acid derivative and application thereof in preparation of medicines for treating LPS-induced inflammation | 五邑大学 | 2024-04-02 | — | — | CN | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4048330-A | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia | SYNTEX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190790-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | AKR1C3 568/4885AKR1C2 1264/4885PTGS2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.