Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352699 | 0.86 | AKR1C3 (0.43) | RXRARXRBRXRGHSD17B1HSD17B2 | |
| SCHEMBL28589581 | 0.85 | PTGS1 (0.46) | SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL508733 | 0.85 | RXRA (0.49) | BCL2L1BADFFAR1RXRARXRB | |
| SCHEMBL2355633 | 0.85 | SHMT1 (0.41) | NPC1RAB9AFFAR1ALDH1A1CNR1 | |
| SCHEMBL2352697 | 0.83 | FFAR1 (0.45) | FFAR1RXRARXRBRXRG | |
| SCHEMBL13366151 | 0.79 | TNKS2 (0.45) | TNKS2BCL2L1BADNPC1RAB9A | |
| SCHEMBL7336718 | 0.78 | HPGD (0.42) | TNKS2BCL2L1BADALDH1A1HSD17B1 | |
| SCHEMBL13922720 | 0.76 | P2RX7 (0.47) | MAPK14RXRARXRBRXRGALDH1A1 | |
| SCHEMBL37438 | 0.75 | TAAR1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29606577 | 0.75 | TAAR1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987500-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| US-8987500-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20140039215-A1 | 4-Biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| US-20140039215-A1 | 4-Biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| US-8586783-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20130018202-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-17 | — | — | US | disclosed |
| US-20130018202-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-17 | — | — | US | disclosed |
| US-8168566-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8168566-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8119566-B2 | use as pesticides and/or herbicides and/or microbicides; for the selective control of weeds; synergistic; low application rates and concentrations; in particular in cereals (especially wheat) | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119566-B2 | use as pesticides and/or herbicides and/or microbicides; for the selective control of weeds; synergistic; low application rates and concentrations; in particular in cereals (especially wheat) | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20120040963-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20120040963-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20080188371-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080188371-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039215-A1 | 4-Biphenyl-substituted pyrazolidin-3,5-dione derivatives | DDT, CYP4X1, HPD | TNKS2 4363/4885BCL2L1 902/4885BAD 1339/4885 |
| US-20120040963-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | TNKS2 4363/4885BCL2L1 902/4885BAD 1339/4885 |
| US-20080188371-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | TNKS2 4363/4885BCL2L1 902/4885BAD 1339/4885 |
| US-20130018202-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | TNKS2 4363/4885BCL2L1 902/4885BAD 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.