SCHEMBL5541932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7189694	0.91	DRD3 (0.51)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL5540652	0.85	DRD3 (0.48)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL2313142	0.82	DRD2 (0.46)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL7934235	0.81	DRD2 (0.43)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL7184376	0.81	DRD2 (0.50)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL9162757	0.79	DRD2 (0.44)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL2177665	0.79	PNMT (0.64)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL24631301	0.78	DRD2 (0.46)	DRD2DRD4DRD3PNMTHTR2B
	SCHEMBL2416249	0.78	LIPG (0.44)	DRD2DRD4DRD3PNMTALDH1A1
	SCHEMBL21694426	0.78	DRD2 (0.48)	DRD2DRD4DRD3PNMTHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.