Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189694 | 0.86 | DRD3 (0.51) | DRD2DRD4DRD3PNMTADRA1A | |
| SCHEMBL5541932 | 0.81 | DRD2 (0.46) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL2313142 | 0.78 | DRD2 (0.46) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL5540652 | 0.78 | DRD3 (0.48) | DRD2DRD4DRD3PNMTADRA1A | |
| SCHEMBL7184376 | 0.77 | DRD2 (0.50) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL9162757 | 0.75 | DRD2 (0.44) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL24631301 | 0.74 | DRD2 (0.46) | DRD2DRD4DRD3PNMTADRA1D | |
| SCHEMBL2416249 | 0.74 | LIPG (0.44) | DRD2DRD4DRD3PNMTALDH1A1 | |
| SCHEMBL21694426 | 0.74 | DRD2 (0.48) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL16792809 | 0.74 | PNMT (0.62) | DRD2DRD4DRD3PNMTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239300-B1 | Metallocene production process | PHILLIPS PETROLEUM COMPANY | 2001-05-29 | — | — | US | disclosed |