Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505316 | 1.00 | MAPT (0.53) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12808522 | 0.83 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6171189 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL14926720 | 0.83 | MAPT (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10101069 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1013781 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6171196 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL18322083 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1508503 | 0.83 | ESR1 (0.60) | MAPTKDM4EKMT2AMEN1CYP1A1 | |
| SCHEMBL3896958 | 0.83 | MAPT (0.54) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1166745-B1 | COSMETICS CONTAINING POLYSACCHARIDE-STEROL DERIVATIVES | NOF CORP (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-20050124652-A1 | Guanidino compounds | BOYCE RUSTUM (US) | 2005-06-09 | — | — | US | disclosed |
| EP-1478626-A2 | GUANIDINO COMPOUNDS | CHIRON CORPORATION (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20030195187-A1 | Guanidino compounds | CHIRON CORPORATION | 2003-10-16 | — | — | US | disclosed |
| WO-2003066597-A2 | GUANIDINO COMPOUNDS | CHIRON CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |
| EP-1166745-A1 | COSMETICS CONTAINING POLYSACCHARIDE-STEROL DERIVATIVES | NOF CORPORATION (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195187-A1 | Guanidino compounds | MC4R, MC2R, GPR4 | MAPT 2811/4885ALDH1A1 4235/4885KDM4E 1204/4885 |
| US-20050124652-A1 | Guanidino compounds | MC4R, MC2R, GPR4 | MAPT 2811/4885ALDH1A1 4235/4885KDM4E 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.