Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330688 | 0.80 | KCNN4 (0.41) | KCNN4TAAR1MAPK1TSHRCYP2C19 | |
| SCHEMBL595615 | 0.79 | KCNN4 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL6086058 | 0.77 | TAAR1 (0.44) | KCNN4TAAR1MAPK1ALDH1A1CYP2C19 | |
| SCHEMBL5328918 | 0.77 | KIF11 (0.41) | KCNN4TAAR1CYP2D6DRD2DRD4 | |
| SCHEMBL1251565 | 0.75 | CYP2C19 (0.41) | KCNN4TAAR1ALDH1A1CYP2C19HIF1A | |
| SCHEMBL5438143 | 0.75 | TSHR (0.46) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL27665654 | 0.74 | TAAR1 (0.52) | KCNN4TAAR1TSHRALDH1A1 | |
| SCHEMBL5738021 | 0.74 | KCNN4 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL739411 | 0.74 | KCNN4 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL1971090 | 0.72 | KCNN4 (0.48) | KCNN4TAAR1MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | claimed |
| EP-1968940-A1 | 3 , 5-SUBSTITUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | Novartis AG (CH) | 2008-09-17 | — | — | EP | claimed |
| EP-1907359-A2 | 3,5-SUBSTITUTED PIPERIDINE DERIVATIVES EFFECTIVE ON RENIN-RELATED DISORDERS | Novartis AG (CH) | 2008-04-09 | — | — | EP | claimed |
| WO-2007077005-A1 | 3 , 5-SUBSTITΓUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | claimed |
| WO-2007006534-A2 | PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | claimed |
| CN-110325582-A | Aqueous dispersion and method for producing aqueous dispersion | ＡＧＣ株式会社 | 2019-10-11 | — | — | CN | disclosed |
| EP-2589643-B1 | HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | SK CHEMICALS CO LTD (KR) | 2017-09-20 | — | — | EP | disclosed |
| US-9142784-B2 | Highly efficient carbazole-based compound, and organic electroluminescence device comprising same | SK CHEMICALS CO., LTD. (KR) | 2015-09-22 | — | — | US | disclosed |
| WO-2014085413-A1 | DISUBSTITUTED OXAZOLIDIN-2-ONES 5-HYDROXYTRYPTAMINE RECEPTOR 2B ACTIVITY MODULATORS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-06-05 | — | — | WO | disclosed |
| EP-2420491-B1 | 3 , 5-SUBSTITUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2013-07-03 | — | — | EP | disclosed |
| US-20130119367-A1 | HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | INDUSTRY ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2013-05-16 | — | — | US | disclosed |
| EP-2589643-A2 | HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | Industry-Academic Cooperation Foundation, Dankook University (KR) | 2013-05-08 | — | — | EP | disclosed |
| CN-1104239-C | Novel N-substituted pyrrolidine derivatives and process for preparing same | KYORIN SEIYAKU KK (JP) | 2003-04-02 | — | — | CN | disclosed |
| CN-1239428-A | Novel N-substituted pyrrolidine derivatives and process for preparing same | KYORIN SEIYAKU KK (JP) | 1999-12-22 | — | — | CN | disclosed |
| EP-0854863-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003951-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| US-4438020-A | CARBONYLATION, HYDROGENATION | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4361706-A | FROM METHANOL, HYDROGEN AND CARBON MONOXIDE IN PRESENCE OF COBALT,IODINE AND PHOSPHORUS COMPOUND | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-11-30 | — | — | US | disclosed |
| US-4352947-A | METHANOL; CARBON MONOXIDE; HYDROGEN; COBALT; IODINE; RUTHENIUM; AND PHOSPHORUS, NITROGEN, OR ARSENIC LIGAND | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | REN, ACE, AGTR1 | KCNN4 239/4885TAAR1 199/4885MAPK1 3136/4885 |
| US-20130119367-A1 | HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | PPIP5K2, INPP5B, EZH2 | KCNN4 351/4885TAAR1 4528/4885MAPK1 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.