SCHEMBL5543906

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5543913	0.83	TRPM8 (0.43)	TRPM8MGAMGAASIMGAM2
	SCHEMBL5546753	0.81	PTGS1 (0.43)	MGAMGAASIMGAM2MAOB
	SCHEMBL5545499	0.80	PTGS2 (0.51)	KMT2APTGS1PTGS2MAPK13MAPK12
	SCHEMBL5537558	0.79	MAPK13 (0.54)	GAAKDM4EMAPTKMT2APTGS1
	SCHEMBL7624713	0.78	PTGS2 (0.59)	TRPM8ADORA2AADORA1KMT2ATP53
	SCHEMBL10263245	0.78	TRPM8 (0.42)	TRPM8MGAMGAASIMGAM2
	SCHEMBL5541453	0.77	ADORA2A (0.43)	TRPM8MGAMGAASIMGAM2
	SCHEMBL9956413	0.77	NOTUM (0.39)	TRPM8MGAMGAASIMGAM2
	SCHEMBL10263340	0.77	L3MBTL1 (0.45)	TRPM8MGAMGAASIMGAM2
	SCHEMBL31194857	0.76	MAPK13 (0.60)	ADORA2AADORA1KMT2APTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.