Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446339 | 0.88 | HPGD (0.59) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL125031 | 0.85 | HPGD (0.56) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL554492 | 0.83 | HPGD (0.54) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL7172322 | 0.83 | HPGD (0.54) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL6208809 | 0.83 | HPGD (0.51) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL8439409 | 0.82 | TSHR (0.46) | HPGDALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL17641437 | 0.81 | CTSD (0.59) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL31321657 | 0.81 | ESR1 (0.66) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL264288 | 0.80 | IRAK4 (0.63) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 | |
| SCHEMBL48968 | 0.80 | HPGD (0.59) | HPGDALDH1A1CTSDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454200-A | Compounds and their use for modulating hemoglobin | 全球血液疗法股份有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-109475555-A | Topical formulations of PDE-4 inhibitors and methods of their use | 德马特科学有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20120053342-A1 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-03-01 | — | — | US | disclosed |
| US-8058469-B2 | Method for making carbamates, ureas and isocyanates | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-11-15 | — | — | US | disclosed |
| EP-2362867-A2 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC Innovative Plastics IP B.V. (NL) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010062490-A2 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-06-03 | — | — | WO | disclosed |
| US-20100113819-A1 | Method for Making Carbamates, Ureas and Isocyanates | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113819-A1 | Method for Making Carbamates, Ureas and Isocyanates | CPS1, ALKBH3, KDM8 | HPGD 1109/4885ALDH1A1 2313/4885CTSD 733/4885 |
| US-20120053342-A1 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | CPS1, ALKBH3, IDH3A | HPGD 1217/4885ALDH1A1 2343/4885CTSD 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.