SCHEMBL5545601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1091403	0.76	ALOX12 (0.38)	CYP1A2CYP2A6TSHRCYP2D6NOS3
	SCHEMBL8860490	0.76	NOS3 (0.43)	ACHETSHRNOS3NPSR1POLB
	SCHEMBL5544284	0.76	NOS3 (0.39)	TSHRNOS3BCL2L1BAD
	SCHEMBL249643	0.76	BCL2L1 (0.48)	CYP1A2TSHRPNMTNOS3BCL2L1
	SCHEMBL5545432	0.76	TSHR (0.36)	TSHRPNMTNOS3BCL2L1BAD
	SCHEMBL5539619	0.76	NOS3 (0.37)	ADRA2ATSHRNOS3HTR5ABCL2L1
	Bromide SCHEMBL11832552	0.74	BCL2L1 (0.47)	CYP1A2TSHRPNMTNOS3BCL2L1
	SCHEMBL301029	0.72	NPC1 (0.41)	HTR5A
	SCHEMBL7019246	0.71	POLB (0.41)	ACHECYP1A2CYP2A6TSHRCYP2D6
	SCHEMBL1525254	0.71	ALDH1A1 (0.47)	ACHETSHRPNMTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.