SCHEMBL5545948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bromide SCHEMBL25306143	0.98	TDP1 (0.50)	TDP1KDM4EMAPTALDH1A1PKM
	SCHEMBL32665220	0.88	NAMPT (0.49)	TDP1KDM4EMAPTALDH1A1PKM
	SCHEMBL3441371	0.81	MAPT (0.57)	TDP1KDM4EMAPTALDH1A1SMYD3
	SCHEMBL2958737	0.81	TDP1 (0.53)	TDP1KDM4EMAPTALDH1A1PKM
	SCHEMBL7041242	0.79	MAPT (0.68)	TDP1KDM4EMAPTALDH1A1PKM
	SCHEMBL8724123	0.79	ADRB1 (0.53)	MAPTALDH1A1SMYD3MEN1KMT2A
	SCHEMBL16669437	0.79	L3MBTL3 (0.44)	SMYD3MEN1KMT2AL3MBTL3L3MBTL1
	SCHEMBL8724121	0.79	L3MBTL1 (0.44)	TDP1KDM4EMAPTALDH1A1SMYD3
	SCHEMBL5545942	0.79	SMYD3 (0.44)	TDP1KDM4EMAPTALDH1A1SMYD3
	SCHEMBL3060190	0.79	HTR3E (0.53)	MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.