Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730061 | 0.82 | L3MBTL3 (0.41) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL3441371 | 0.81 | MAPT (0.57) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL8338229 | 0.79 | LTA4H (0.44) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL5545948 | 0.79 | TDP1 (0.51) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL377434 | 0.79 | ALDH1A1 (0.59) | L3MBTL1L3MBTL3KMT2AMEN1TSHR | |
| SCHEMBL8724123 | 0.79 | ADRB1 (0.53) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL16669437 | 0.79 | L3MBTL3 (0.44) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL5545942 | 0.79 | SMYD3 (0.44) | L3MBTL1L3MBTL3SMYD3KMT2AMEN1 | |
| SCHEMBL3060190 | 0.79 | HTR3E (0.53) | L3MBTL1L3MBTL3KMT2AMEN1ALOX15 | |
| SCHEMBL6747861 | 0.79 | USP2 (0.58) | L3MBTL1L3MBTL3KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5681954-A | HAS CALMODULIN INHIBITORY ACTIVITY; USEFUL IN TREATING DISEASES OF THE CIRCULATORY ORGANS OR IN CEREBRAL REGION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |