Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029858 | 0.81 | TBXA2R (0.32) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL5544419 | 0.78 | MAPK14 (0.39) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL907710 | 0.77 | EPHX2 (0.38) | EPHX2MGLLTOP2ATOP2BKDM4E | |
| Formaldehyde SCHEMBL5544617 | 0.76 | MAPK14 (0.38) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL7411090 | 0.76 | NPC1 (0.32) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL5549490 | 0.72 | NSD2 (0.36) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL1361477 | 0.72 | SLC6A4 (0.37) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL2347668 | 0.69 | EPHX2 (0.32) | EPHX2TBXA2RCYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4085361 | 0.69 | TOP2A (0.40) | EPHX2MGLLTOP2ATOP2BKDM4E | |
| SCHEMBL14255710 | 0.69 | EPHX2 (0.40) | EPHX2TBXA2RMGLLCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298124-B1 | Method For the Preparation of Citalopram | LUNDBECK & CO AS H (DK) | 2007-02-28 | — | — | EP | disclosed |
| EP-1228056-B1 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2004-09-22 | — | — | EP | disclosed |
| EP-1298124-A1 | Method For the Preparation of Citalopram | H. Lundbeck A/S (DK) | 2003-04-02 | — | — | EP | disclosed |
| US-20020177722-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-11-28 | — | — | US | disclosed |
| EP-1228056-A2 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. LUNDBECK A/S (DK) | 2002-08-07 | — | — | EP | disclosed |
| US-6407267-B1 | USING GRIGNARD REAGENT; ANTIDEPRESSANT | H. LUNDBECK A/S (DK) | 2002-06-18 | — | — | US | disclosed |
| US-20020035277-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-03-21 | — | — | US | disclosed |
| WO-2000012044-A2 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. LUNDBECK A/S (DK) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177722-A1 | Method for the preparation of citalopram | HTR6, HTR1A, HTR3C | NPC1 1974/4885CASP3 1437/4885RAB9A 3360/4885 |
| US-20020035277-A1 | Method for the preparation of citalopram | HTR6, HTR1A, HTR1F | NPC1 2148/4885CASP3 1738/4885RAB9A 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.