SCHEMBL554687

SCHEMBL554687

CC(C)(C)c1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
MAPT P10636 6/20 1.00
RAB9A P51151 3/20 1.00
NPC1 O15118 2/20 1.00
MAPK1 P28482 2/20 1.00
HPGD P15428 1/20 1.00
TDP1 Q9NUW8 4/20 0.64
CYP3A4 P08684 3/20 0.64
TSHR P16473 1/20 0.64
POLB P06746 2/20 0.62
KDM4E B2RXH2 1/20 0.62
TEAD4 Q15561 1/20 0.58
MAOA P21397 2/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAOB P27338 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MITF O75030 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4985761 0.94 ALDH1A1 (0.88) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL427816 0.88 RAB9A (0.77) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL18118972 0.88 RAB9A (0.77) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL127279 0.88 RAB9A (0.77) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL204685 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL311555 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL5071236 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL2677985 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL49650 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL13836578 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9ANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3332783-B1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-12-04 EP claimed
CN-117164855-A High-cohesiveness branched polyimide polymer and preparation method thereof 江苏环峰电工材料有限公司 2023-12-05 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN claimed
EP-3332783-A1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2018-06-13 EP claimed
EP-2793884-A1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS Ecole Polytechnique Federale de Lausanne (EPFL) (CH) 2014-10-29 EP claimed
WO-2013093885-A1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2013-06-27 WO claimed
EP-3797991-B1 PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-10-29 EP disclosed
US-12448510-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2025-10-21 US disclosed
EP-3995536-B1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-06-18 EP disclosed
EP-3332783-B1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-12-04 EP disclosed
CN-119019324-A Process for preparing aminodiaryl ethers and aminodiaryl ether hydrochlorides 塞莱斯蒂亚生物技术股份公司 2024-11-26 CN disclosed
US-12030855-B2 Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts CELLESTIA BIOTECH AG (CH) 2024-07-09 US disclosed
US-20240166798-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-05-23 US disclosed
EP-0816914-A2 Diazonium salt for thermosensitive recording medium Oki Electric Industry Co., Ltd. (JP) 1998-01-07 EP disclosed
US-4745052-A Color photographic recording material containing 2-equivalent magenta couplers AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4501592-A Anthraquinone dyes, process for their preparation, and use thereof CIBA-GEIGY CORPORATION (US) 1985-02-26 US disclosed
EP-0113922-A2 Process for the manufacture of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030855-B2 Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts ADH1C, ADH1A, DDC ALDH1A1 42/4885MAPT 2229/4885RAB9A 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.