SCHEMBL554697

SCHEMBL554697

Clc1ccc(C2=NNCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 2/20 0.43
SIGMAR1 Q99720 1/20 0.41
HTR2C P28335 4/20 0.40
LMNA P02545 2/20 0.40
RECQL P46063 1/20 0.40
NOTUM Q6P988 1/20 0.39
HTR2A P28223 3/20 0.39
HTR2B P41595 3/20 0.39
HTR7 P34969 2/20 0.39
HTR6 P50406 2/20 0.39
HTR3A P46098 1/20 0.39
HTR1D P28221 1/20 0.38
HTR1E P28566 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SOS1 Q07889 1/20 0.37
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28999660 0.98 HTR2C (0.43) KDRSIGMAR1HTR2CLMNARECQL
SCHEMBL7763318 0.83 LMNA (0.36) KDRLMNANPC1RAB9AMEN1
SCHEMBL3325615 0.79 QDPR (0.41) LMNARECQLNPC1RAB9APOLB
SCHEMBL6771534 0.79 HTR2A (0.38) HTR2CLMNAHTR2AHTR2BHTR7
SCHEMBL6768059 0.79 KDR (0.43) KDRHTR2CLMNAHTR2AHTR2B
SCHEMBL4627244 0.79 HTR2C (0.41) HTR2CNPC1RAB9APOLBMEN1
SCHEMBL972816 0.78 SMN1; SMN2 (0.52) KDRSIGMAR1HTR2CLMNAHTR7
SCHEMBL17838640 0.75 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL9009115 0.71 PTGS2 (0.50)
SCHEMBL10964893 0.71 DRD1 (0.41) LMNANPC1RAB9APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164272-A Concrete brightening agent and preparation method thereof 云南森博混凝土外加剂有限公司 2023-12-05 CN claimed
CN-117164305-A Mirror concrete and preparation method thereof 云南森博混凝土外加剂有限公司 2023-12-05 CN claimed
US-11561083-B2 Secondary battery and apparatus and method for measuring dimension of secondary battery LG ENERGY SOLUTION, LTD. (KR) 2023-01-24 US claimed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US claimed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US claimed
EP-4745232-A2 PROTEASE VARIANTS WITH IMPROVED PERFORMANCE Henkel AG & Co. KGaA (DE) 2026-05-20 EP disclosed
US-20260132396-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS HENKEL AG & CO KGAA (DE) 2026-05-14 US disclosed
EP-4143289-B1 HIGHLY ALKALINE TEXTILE WASHING AGENT COMPRISING PROTEASE HENKEL AG & CO KGAA (DE) 2026-05-06 EP disclosed
EP-4728036-A1 PEPTIDES WITH DIRT-RELEASING EFFECT FOR DETERGENTS AND CLEANING AGENTS Henkel AG & Co. KGaA (DE) 2026-04-22 EP disclosed
US-12492360-B2 Highly alkaline textile washing agent comprising protease HENKEL AG & CO. KGAA (DE) 2025-12-09 US disclosed
EP-4649127-A1 ENZYME-CONTAINING DETERGENTS AND CLEANING AGENTS Henkel AG & Co. KGaA (DE) 2025-11-19 EP disclosed
US-20250346835-A1 DETERGENT AND CLEANING AGENT WITH IMPROVED ENZYME STABILITY HENKEL AG & CO KGAA (DE) 2025-11-13 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed
WO-2007019933-A1 1-ACYLDIHYDROPYRAZOL DERIVATIVES MERCK PATENT GMBH (DE) 2007-02-22 WO disclosed
US-6831083-B2 For therapy and prophylaxis of cerebral ischemia (cerebral infarct and brain edema), sequela of cerebral ischemia, cephalotrauma, glaucoma, retinopathy, epilepsy and amyotrophic lateral sclerosis (ALS), all caused by glutamic acid toxicity MITSUI CHEMICALS, INC. (JP) 2004-12-14 US disclosed
US-20030149046-A1 Pyrazoline derivative or tetrahydropyridazine derivative and medicinal use thereof MITSUI CHEMICALS, INC. (JP) 2003-08-07 US disclosed
EP-1270567-A1 PYRAZOLINE DERIVATIVES OR TETRAHYDROPYRIDAZINE DERIVATIVES AND MEDICINAL USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-01-02 EP disclosed
US-4140792-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed
US-4140787-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149046-A1 Pyrazoline derivative or tetrahydropyridazine derivative and medicinal use thereof SLC1A2, SLC1A1, SLC1A3 KDR 606/4885SIGMAR1 3128/4885HTR2C 2262/4885
US-20260132396-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS CTRL, DPEP1, MME KDR 4005/4885SIGMAR1 3450/4885HTR2C 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.