Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL25335049 | 0.74 | L3MBTL1 (0.77) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL2490829 | 0.70 | L3MBTL1 (0.69) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| Piperazine SCHEMBL28152024 | 0.69 | CES2 (0.53) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL4088787 | 0.68 | L3MBTL1 (0.71) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| Piperazine SCHEMBL28148055 | 0.68 | CES2 (0.52) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL1462616 | 0.67 | LMNA (0.95) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL29360523 | 0.67 | LMNA (0.95) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL673571 | 0.67 | LMNA (0.95) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL674979 | 0.67 | LMNA (0.95) | KMT2AL3MBTL1LMNANAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL29480469 | 0.67 | LMNA (0.95) | KMT2AL3MBTL1LMNANAPRTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196080-B2 | Respiratory system disordeers; chronic obstructive pulminary disease | ASTELLAS PHARMA INC. (JP) | 2007-03-27 | — | — | US | disclosed |