SCHEMBL5548770

SCHEMBL5548770

CCCC[Sn](CCCC)(Oc1ccc([N+](=O)[O-])cc1)O[Sn](CCCC)(CCCC)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.48
BCL9 O00512 1/20 0.47
CTNNB1 P35222 1/20 0.47
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 5/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
PTGS2 P35354 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5548753 0.76 KCNH2 (0.36) ALDH1A1CYP3A4HSD17B10TSHRNPC1
SCHEMBL2565246 0.75 MAPT (0.67) MGLLBCL9CTNNB1ALDH1A1MAPT
SCHEMBL465078 0.75 LTA4H (0.44) ALDH1A1CYP3A4MAPK1MAPTLMNA
SCHEMBL2922658 0.74 MAPT (0.51) MGLLBCL9CTNNB1ALDH1A1HSD17B10
SCHEMBL1240044 0.72 MAPT (0.63) MGLLMAPTPTGS2NPC1RAB9A
SCHEMBL10537771 0.72 ALDH1A1 (0.47) MGLLALDH1A1CYP3A4MAPK1HSD17B10
SCHEMBL11512630 0.71 BCL9 (0.63) MGLLBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL5049067 0.71 MAPT (0.62) MGLLTSHRMAPTPTGS2NPC1
SCHEMBL9308071 0.71 MAPT (0.62) MGLLTSHRMAPTPTGS2NPC1
SCHEMBL51004 0.71 MAPT (0.62) MGLLTSHRMAPTPTGS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890596-B1 Process for the preparation of poly (arylcarbonate)s GEN ELECTRIC (US) 2007-12-05 EP claimed