Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypoxanthine SCHEMBL7037918 | 0.70 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL25381 | 0.70 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL30096461 | 0.70 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2008437 | 0.69 | LMNA (0.57) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL560392 | 0.68 | ALDH1A1 (0.95) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL160505 | 0.68 | ALDH1A1 (0.54) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL7168422 | 0.68 | ALDH1A1 (0.95) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL2639254 | 0.68 | ALDH1A1 (0.95) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL122843 | 0.68 | ALDH1A1 (0.95) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL3895 | 0.68 | ALDH1A1 (0.54) | ALDH1A1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142317-A1 | Topical composition for treatment of skin disorders | QLT USA, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142317-A1 | Topical composition for treatment of skin disorders | CDA, ADA, DCTD | ALDH1A1 620/4885PI4KA 3462/4885PI4K2B 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.