Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.49 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.49 |
| ▸ | BCL6 | P41182 | 2/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | GALR1 | P47211 | 4/20 | 0.43 |
| ▸ | GALR2 | O43603 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5432850 | 0.99 | EHMT2 (0.48) | EHMT2EHMT1BCL6IDH2GALR1 | |
| SCHEMBL4829436 | 0.98 | EHMT2 (0.50) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Bromide SCHEMBL6016985 | 0.97 | EHMT2 (0.49) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Hydrochloric Acid SCHEMBL5550552 | 0.97 | EHMT2 (0.49) | EHMT2EHMT1BCL6IDH2GALR1 | |
| SCHEMBL6856715 | 0.95 | EHMT2 (0.54) | EHMT2EHMT1BCL6IDH2GALR1 | |
| SCHEMBL4839206 | 0.94 | BCL6 (0.50) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Malonic Acid SCHEMBL4829481 | 0.92 | EHMT2 (0.45) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Succinic Acid SCHEMBL4835600 | 0.91 | EHMT2 (0.44) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Maleic Acid SCHEMBL4835112 | 0.91 | EHMT2 (0.44) | EHMT2EHMT1BCL6IDH2GALR1 | |
| Fumaric Acid SCHEMBL4836755 | 0.91 | EHMT2 (0.44) | EHMT2EHMT1BCL6IDH2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169784-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050137196-A1 | Medical devices employing triazine compounds and compositions thereof | NATIONAL BANK OF CANADA (CA) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137196-A1 | Medical devices employing triazine compounds and compositions thereof | PTGIS, AREG, TGFB1 | EHMT2 2474/4885EHMT1 2630/4885BCL6 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.