Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926945 | 0.91 | HTR2A (0.38) | HTR2AALDH1A1MAPTCYP1A2KDM4E | |
| SCHEMBL5554772 | 0.73 | KDM4C (0.33) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL5556439 | 0.72 | SLC9A1 (0.36) | ALDH1A1KMT2AMAPTHPGDKDM4E | |
| SCHEMBL7902827 | 0.72 | KDM4E (0.44) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7911288 | 0.71 | PLA2G4B (0.42) | ALDH1A1KMT2AMAPTHPGDKDM4E | |
| SCHEMBL7911289 | 0.71 | ALDH1A1 (0.34) | ALDH1A1KMT2AMAPTHPGDKDM4E | |
| SCHEMBL5017678 | 0.71 | HTR2A (0.50) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL6397367 | 0.70 | HTR2A (0.49) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL29550444 | 0.68 | HTR2A (0.50) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL6816689 | 0.68 | SIGMAR1 (0.52) | HTR2AKMT2ABCL9CTNNB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849774-A1 | CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME | TOA EIYO LTD. (JP) | 2007-10-31 | — | — | EP | disclosed |