Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876496 | 0.77 | HTT (0.42) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5549673 | 0.77 | CDK2 (0.59) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL11919296 | 0.72 | L3MBTL1 (0.61) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL22715212 | 0.71 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL15457568 | 0.71 | HTT (0.47) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL8725004 | 0.71 | HTT (0.39) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL1271646 | 0.70 | CDK1 (0.56) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL12474436 | 0.69 | CDK1 (0.54) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL9879120 | 0.68 | HTT (0.63) | HTTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL3700683 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016006974-A2 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2016-01-14 | — | — | WO | disclosed |
| WO-2012064674-A1 | MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS | ABBOTT LABORATORIES (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120115244-A1 | MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS | ABBOTT LABORATORIES (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115244-A1 | MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS | ABBOTT LABORATORIES (US) | 2012-05-10 | — | — | US | disclosed |
| EP-0759927-B1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | US GOV HEALTH & HUMAN SERV (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5612468-A | GENETIC ENGINEERING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0759927-A1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5525711-A | MONOMERS FOR DNA AMPLIFICATION PROCEDURES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995031469-A1 | PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115244-A1 | MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS | SPR, CD68, CMKLR2 | HTT 2791/4885ALDH1A1 2660/4885KMT2A 4072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.