Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271646 | 0.75 | CDK1 (0.56) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL12474436 | 0.73 | CDK1 (0.54) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL22715212 | 0.71 | ALDH1A1 (0.65) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL5551189 | 0.67 | HTT (0.47) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL11683430 | 0.67 | ALDH1A1 (0.42) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| Sulfuric Acid SCHEMBL21495047 | 0.67 | CDK1 (0.47) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL11683196 | 0.67 | ALDH1A1 (0.42) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL4570268 | 0.67 | PNP (0.46) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL3700681 | 0.67 | ALDH1A1 (0.30) | ALDH1A1L3MBTL1 | |
| SCHEMBL5181913 | 0.63 | PNP (0.48) | ALDH1A1MEN1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| EP-2440533-B1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA SCIENCES ET GÉNIE S E C (CA) | 2015-09-23 | — | — | EP | disclosed |
| EP-2440533-B1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA SCIENCES ET GÉNIE S E C (CA) | 2015-09-23 | — | — | EP | disclosed |
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | UNIVERSITE DE SHERBROOKE (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | UNIVERSITE DE SHERBROOKE (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | UNIVERSITE DE SHERBROOKE (CA) | 2015-06-04 | — | — | US | disclosed |
| US-8247551-B2 | Lead sensor and methods of use | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S.E.C. (CA) | 2012-05-17 | — | — | US | disclosed |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S.E.C. (CA) | 2012-05-17 | — | — | US | disclosed |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S.E.C. (CA) | 2012-05-17 | — | — | US | disclosed |
| US-7888506-B2 | include a conjugated ring system, such as a dithiolone, a pyran, and a pyrazine containing ring system; biomarker applications, pH sensors, metal sensors, and as components for molecular electronics | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2011-02-15 | — | — | US | disclosed |
| WO-2010142027-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S. E. C. (CA) | 2010-12-16 | — | — | WO | disclosed |
| US-20100041158-A1 | Lead sensor and methods of use | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2010-02-18 | — | — | US | disclosed |
| US-20080182337-A1 | COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF FLUOROPHORES | DUQUESNE UNIVERSITY (US) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | GDA, RNMT, GNPDA1 | ALDH1A1 1272/4885MEN1 4129/4885MAPT 4810/4885 |
| US-20080182337-A1 | COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF FLUOROPHORES | PFAS, PPOX, DHPS | ALDH1A1 1098/4885MEN1 2741/4885MAPT 3036/4885 |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | GDA, RNMT, GNPDA1 | ALDH1A1 1272/4885MEN1 4129/4885MAPT 4810/4885 |
| US-20100041158-A1 | Lead sensor and methods of use | CACYBP, NCS1, PDLIM5 | ALDH1A1 2595/4885MEN1 3848/4885MAPT 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.