Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562071 | 0.74 | RAB9A (0.35) | MAPTALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL9392813 | 0.71 | P2RY6 (0.41) | MAPTALDH1A1SMN1; SMN2CYP3A4CA1 | |
| SCHEMBL133893 | 0.69 | NPC1 (0.66) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL6581336 | 0.69 | KDM4E (0.67) | MAPTALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL31019604 | 0.69 | NPC1 (0.66) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL8760125 | 0.69 | CASP6 (0.62) | MAPTALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL67998 | 0.68 | P2RY6 (0.33) | — | |
| SCHEMBL20166666 | 0.67 | SMYD3 (0.60) | ALDH1A1SMN1; SMN2KDM4EMPOCYP3A4 | |
| SCHEMBL21625555 | 0.67 | CTSD (0.63) | MAPTALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL2648700 | 0.67 | MAPK1 (0.58) | MAPTALDH1A1SMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131310-A1 | ANTI-INFLAMMATORY AND ANALGESIC PHARMACEUTICAL COMPOSITION CONTAINING SAFROLE N-ACYLHYDRAZONE DERIVATIVES, USE, AND METHOD OF PREPARATION | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2007-11-22 | — | — | WO | disclosed |