Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.45 |
| ▸ | CHRNG | P07510 | 2/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.45 |
| ▸ | CHRND | Q07001 | 2/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL5551574 | 0.81 | HTT (0.51) | GRIN1GRIN2AGRIN2BHTT | |
| Benzoic Acid SCHEMBL5547336 | 0.81 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2BGRIA1HTT | |
| Phenylacetic Acid SCHEMBL1832667 | 0.80 | AKR1B1 (0.68) | AKR1B1RENNPC1HTTRAB9A | |
| Phenylacetic Acid SCHEMBL1835383 | 0.80 | AKR1B1 (0.74) | AKR1B1HTT | |
| SCHEMBL5551164 | 0.79 | HTT (0.47) | GRIN1GRIN2AGRIN2BNPC1HTT | |
| Phenol SCHEMBL5552828 | 0.79 | LMNA (0.46) | GRIN1GRIN2AGRIN2BSMN1; SMN2 | |
| Glycolic Acid SCHEMBL5552670 | 0.78 | ALOX15 (0.52) | SMN1; SMN2 | |
| Bicarbonate SCHEMBL5551073 | 0.78 | CA12 (0.56) | SMN1; SMN2 | |
| Bicarbonate SCHEMBL5552761 | 0.78 | CA12 (0.56) | SMN1; SMN2 | |
| Spermine SCHEMBL27604705 | 0.78 | SIGMAR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |