Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.91 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.91 |
| ▸ | LMNA | P02545 | 4/20 | 0.86 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iohexol SCHEMBL26501 | 0.95 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL31722694 | 0.95 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL8844889 | 0.95 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL37920 | 0.95 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL8711982 | 0.94 | CYP2C19 (0.97) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL22645199 | 0.94 | LMNA (0.97) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL22719758 | 0.93 | CYP2C19 (0.95) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL3666605 | 0.93 | CYP2C19 (0.95) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL37712 | 0.93 | LMNA (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL8845042 | 0.93 | LMNA (1.00) | CYP2C19HIF1ALMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | claimed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | claimed |
| US-4816168-A | TUBES FOR BLOOD SEPARATION | BECTON DICKINSON & COMPANY (US) | 1989-03-28 | — | — | US | claimed |
| US-4640785-A | Separation of lymphocytes and monocytes from blood samples | BECTON DICKINSON AND COMPANY (US) | 1987-02-03 | — | — | US | claimed |
| CN-117460995-A | Composition for forming underlayer film of silicon-containing resist | 日产化学株式会社 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023117667-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOISOPHTHALIC BISAMIDES | BRACCO IMAGING SPA (IT) | 2023-06-29 | — | — | WO | disclosed |
| CN-114340531-A | Devices, systems, and methods for assisting balloon ablation | 皇家飞利浦有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108261561-B | Developable hyaluronic acid microsphere embolic agent as well as preparation method and application thereof | 杭州协合医疗用品有限公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-112601557-A | Cell-based assays for measuring the efficacy of pharmaceutical products | 诺华股份有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-103356206-A | System and method for contrast agent estimation in X-ray imaging | GEN ELECTRIC | 2013-10-23 | — | — | CN | disclosed |
| CN-102816085-B | Preparation method of iohexol impurity | ZHEJIANG STARRY PHARMACEUTICAL CO LTD | 2013-08-14 | — | — | CN | disclosed |
| CN-102816085-A | Preparation method of iohexol impurity | ZHEJIANG STARRY PHARMACEUTICAL CO LTD | 2012-12-12 | — | — | CN | disclosed |
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| US-5349085-A | IODIXANOL; 1,3-bis(acetylamino)-N,N'-bis(3,5-bis(2,3dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl)-2-hydroxypropane | NYCOMED IMAGING AS (NO) | 1994-09-20 | — | — | US | disclosed |
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |
| US-4640785-A | Separation of lymphocytes and monocytes from blood samples | BECTON DICKINSON AND COMPANY (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0190488-A1 | Separation of lymphocytes and monocytes from blood samples | Becton, Dickinson and Company (US) | 1986-08-13 | — | — | EP | disclosed |
| EP-0108638-B1 | X-RAY CONTRAST AGENTS | NYEGAARD & CO. A/S (NO) | 1986-07-16 | — | — | EP | disclosed |
| EP-0108638-A1 | X-ray contrast agents | NYEGAARD & CO. A/S (NO) | 1984-05-16 | — | — | EP | disclosed |