SCHEMBL555423

SCHEMBL555423

Cc1ccccc1C(O)(C(=O)O)C(O)(C(=O)O)c1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 2/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CHRM3 P20309 1/20 0.37
MYC P01106 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8139523 0.98 HPGD (0.40) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL30032075 0.88 PDK1 (0.42) CYP2C9ALDH1A1KDM4EGAAATM
SCHEMBL1826833 0.81 GABRA1 (0.41) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL31503044 0.80 TSHR (0.39) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL20563882 0.80 MYC (0.42) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL3633862 0.78 GABRA1 (0.42) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL2792373 0.78 CYP2C9 (0.55) HPGDCYP2C9ALDH1A1GAANPSR1
Ammonia Solution, Strong SCHEMBL28714249 0.77 GABRA1 (0.41) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL7186121 0.77 CYP1A2 (0.43) HPGDCYP2C9ALDH1A1KDM4EGAA
SCHEMBL17420628 0.77 PDK1 (0.42) HPGDALDH1A1KDM4EGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420658-B Preparation method of chiral triazine compound 天津辰欣药物研究有限公司 2024-09-20 CN claimed
CN-118420658-A Preparation method of chiral triazine compound 天津辰欣药物研究有限公司 2024-08-02 CN claimed
CN-117946102-A Non-nefardone diastereomer salt and method for preparing non-nefardone by using same 江苏德源药业股份有限公司 2024-04-30 CN claimed
WO-2007075630-A1 METHOD FOR PRODUCING 3-AMINOPIPERIDINE DIASTEREOMER DOW GLOBAL TECHNOLOGIES INC. (US) 2007-07-05 WO claimed
US-20250177349-A1 ARYL ALKYNAMIDE DERIVATIVES Astellas Engineered Small Molecules US, Incorporated 2025-06-05 US disclosed
CN-119768398-A Heterocyclic compounds which inhibit and/or induce KRAS protein degradation 安斯泰来制药有限公司 2025-04-04 CN disclosed
WO-2025068950-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2025-04-03 WO disclosed
CN-119451569-A Preparation method of non-human primate model for cerebral infarction and pharmaceutical composition for cerebral infarction treatment 安斯泰来制药株式会社 2025-02-14 CN disclosed
CN-119317620-A Azacycloalkyl carbonyl cyclic amine compounds 亚力维克希斯股份有限公司 2025-01-14 CN disclosed
EP-4486720-A1 ARYL ALKYNAMIDE DERIVATIVES Astellas Pharma, Inc. (JP) 2025-01-08 EP disclosed
CN-119110802-A Heterocyclic derivatives substituted with a middle or macrocyclic benzyl group and related uses 森特萨制药(英国)有限公司 2024-12-10 CN disclosed
CN-113365994-B Pyridazinyl thiazole carboxamides 安斯泰来制药株式会社 2024-08-09 CN disclosed
US-3976778-A ANTHELMINTIC, BACTERICIDE, ANTIPROTOZOA CIBA-GEIGY CORPORATION (US) 1976-08-24 US disclosed
US-3974280-A Benzothiophenes CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed
US-3973024-A Analgesic and anti-inflammatory anilino-phenylacetic acid-(2,3 or 4 pyridyl)-methyl esters and derivatives CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3956335-A HYPERTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3949088-A Substituted phenoxy propanol amines used for treating cardiovascular diseases SAMUELSSON BENNY ROGER 1976-04-06 US disclosed
US-3944589-A α-Cycloalkenylphenyl-fatty acid nitriles CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3935259-A 2-HYDROXY-3-(UREIDOPHENOXY)PROPYL, CARDIAC BETA RECEPTOR INHIBITORS CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3933802-A New sulphamoylbenzoic acid amides CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177349-A1 ARYL ALKYNAMIDE DERIVATIVES STING1, IRF3, TBK1 HPGD 3987/4885CYP2C9 4741/4885ALDH1A1 3269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.