Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604098 | 0.71 | MEN1 (0.58) | — | |
| SCHEMBL5559216 | 0.71 | ACHE (0.41) | ACHEMAP4K4 | |
| SCHEMBL2357821 | 0.68 | ADORA2A (0.57) | ADORA1ADORA2A | |
| SCHEMBL11200730 | 0.63 | KDM4E (0.49) | — | |
| SCHEMBL2303521 | 0.63 | ADORA2A (0.82) | ADORA1ADORA2A | |
| SCHEMBL1604858 | 0.63 | SIGMAR1 (0.46) | ACHEMAP4K4 | |
| SCHEMBL8108284 | 0.63 | SIGMAR1 (0.46) | ACHEMAP4K4 | |
| SCHEMBL11197383 | 0.62 | ADORA2A (0.39) | ADORA1ADORA2A | |
| SCHEMBL3298977 | 0.62 | ADORA2A (0.61) | ADORA1ADORA2A | |
| SCHEMBL5559357 | 0.61 | CHRNB2 (0.45) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |