Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605065 | 0.73 | MEN1 (0.54) | ACHEMEN1KMT2A | |
| SCHEMBL5554340 | 0.71 | ADORA1 (0.40) | ACHEMAP4K4 | |
| SCHEMBL8108284 | 0.60 | SIGMAR1 (0.46) | ACHEMAP4K4MEN1KMT2A | |
| SCHEMBL1604858 | 0.60 | SIGMAR1 (0.46) | ACHEMAP4K4MEN1KMT2A | |
| SCHEMBL8552184 | 0.60 | DRD4 (0.61) | ACHESSTR5DRD2DRD4DRD3 | |
| SCHEMBL6981484 | 0.59 | DRD2 (0.58) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL10556550 | 0.59 | MEN1 (0.61) | ACHEDRD2DRD3BCHEMEN1 | |
| SCHEMBL2169088 | 0.59 | DCPS (0.78) | — | |
| SCHEMBL2673348 | 0.58 | CXCR4 (0.47) | ACHEMAP4K4 | |
| SCHEMBL8108384 | 0.58 | BCHE (0.55) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |