SCHEMBL5555756

SCHEMBL5555756

OB(O)Oc1c2ccccc2c(-c2cccc3ccccc23)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.39
ADK P55263 1/20 0.39
DHFR P00374 1/20 0.37
TYMP P19971 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
SOS1 Q07889 1/20 0.35
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
PPARG P37231 4/20 0.33
PPARA Q07869 4/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
PTPN1 P18031 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPARD Q03181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542925 1.00 GSK3B (0.39) GSK3BADKDHFRTYMPMEN1
SCHEMBL1207137 0.83 CRHBP (0.41) KMT2ACYP1A2CYP2C9KDM4E
Boric Acid SCHEMBL28232822 0.83 CYP1A2 (0.44) GSK3BADKDHFRTYMPMEN1
SCHEMBL30761753 0.81 TRPM4 (0.40) MEN1KMT2ACYP1A2SOS1GPR84
SCHEMBL30807904 0.81 PPARG (0.42) GSK3BADKDHFRHDAC8HDAC6
SCHEMBL15887506 0.80 DHFR (0.42) GSK3BADKDHFRTYMPMEN1
SCHEMBL5555759 0.79 ALDH1A1 (0.35) MEN1KMT2AHDAC8HDAC6GPR84
SCHEMBL30968172 0.79 GPR84 (0.35) MEN1KMT2AHDAC8HDAC6GPR84
SCHEMBL702934 0.79 ALDH1A1 (0.50) GSK3BADKDHFRTYMPMEN1
SCHEMBL29407412 0.79 ALDH1A1 (0.50) GSK3BADKDHFRTYMPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed