SCHEMBL5555759

SCHEMBL5555759

OB(O)Oc1c2ccccc2c(-c2ccccc2-c2ccccc2)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
BCL2L1 Q07817 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
GPR84 Q9NQS5 2/20 0.35
RAB9A P51151 1/20 0.33
RCE1 Q9Y256 1/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MAPT P10636 1/20 0.33
MPI P34949 1/20 0.33
HNF4A P41235 1/20 0.33
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968172 0.90 GPR84 (0.35) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
SCHEMBL2447870 0.85 ACHE (0.38) ALDH1A1HPGDGPR84KDM4EKMT2A
SCHEMBL5556127 0.82 MGLL (0.41) ALDH1A1HPGDBCL2L1KDM4EMAPT
SCHEMBL30542925 0.79 GSK3B (0.39) HDAC8HDAC6GPR84KDM4EMEN1
SCHEMBL30937737 0.79 MGLL (0.35) ALDH1A1GPR84PDE4BPDE4APDE4C
SCHEMBL5555756 0.79 GSK3B (0.39) HDAC8HDAC6GPR84KDM4EMEN1
SCHEMBL5858791 0.79 ESR1 (0.36) ALDH1A1HPGDHSD17B10KDM4EMEN1
SCHEMBL1207137 0.77 CRHBP (0.41) ALDH1A1HPGDHSD17B10KDM4EKMT2A
SCHEMBL4826724 0.77 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
SCHEMBL261327 0.77 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10BCL2L1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed