Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240871 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1KMT2ACTSDMEN1 | |
| SCHEMBL5557636 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1KMT2ACTSDMEN1 | |
| SCHEMBL5557796 | 0.91 | CTSD (0.35) | KDM4EALDH1A1KMT2ACTSDMEN1 | |
| SCHEMBL5556455 | 0.81 | CTSB (0.47) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL5556739 | 0.80 | MMP2 (0.41) | CTSDPTPN1MMP2MMP9MMP8 | |
| SCHEMBL5558759 | 0.78 | MEN1 (0.37) | KDM4EALDH1A1KMT2ACTSDMEN1 | |
| SCHEMBL5556660 | 0.78 | MMP2 (0.50) | PTPN1MMP2MMP9MMP8MMP1 | |
| SCHEMBL5557500 | 0.77 | MMP2 (0.47) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL6245527 | 0.77 | MMP2 (0.47) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL5552331 | 0.77 | MMP2 (0.47) | MMP2MMP9MMP8MMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | KDM4E 3630/4885ALDH1A1 4059/4885KMT2A 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.